The Uncharted Link Between Desogestrel and Hypercalcemia

This report presents a unique case of hypercalcemia with an elusive etiology. A 37-year-old Caucasian female history gonadotropin-secreting pituitary microadenoma and recurrent nephrolithiasis was found to have hypercalcemia, hypercalciuria, elevated 1,25-dihydroxyvitamin D levels, low parathyroid hormone levels. Extensive investigations were conducted identify the cause, including ruling out sarcoidosis other granulomatous disorders. Imaging diagnostic testing revealed normal results. The patient’s condition considerably improved after cessation oral contraceptive pill containing desogestrel. surprising association raises possibility that use desogestrel could result in as one side effects. To ensure proper care avoid consequences linked severe high index suspicion is needed detect underlying cause even absence usual indications.